Physician Muneeba Shaikh reviews the X-ray results of a patient who is participating in the endTB-Q clinical trial at the endTB clinic run by Interactive Research & Development in Kotri. Pakistan, 2024. © Asim Hafeez
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Leaders’ failure to fully replenish Global Fund threatens decades of progress against HIV, TB, and malaria

The funding target must be met this week to prevent catastrophic cuts and soaring costs for patients who can’t afford to pay high prices for medicines.

Ahead of the Global Fund to Fight AIDAs, Tuberculosis (TB) and Malaria’s Eighth Replenishment Summit in Johannesburg, Doctors Without Borders/Médecins Sans Frontières (MSF) is calling for world leaders to meet the Global Fund’s 18 billion USD ($25 billion Canadian) target.  

Failure to meet this goal risks catastrophic cuts to essential services, threatens the resurgence of HIV, tuberculosis (TB) and malaria and forces the financial burden of healthcare onto the world’s most at-risk patients. 

The high-level fundraising meeting, will take place on Friday, Nov. 21, on the margins of the G20 Leaders’ Summit. For this three-year funding cycle (2027–2029), there is a high risk the Global Fund may receive pledges several billion below the target required to respond impactfully to HIV, TB and malaria, Its possible it will fall even billions below the last replenishment of 15 billion USD ($21 billion Canadian), which still fell drastically short of the funding needed to tackle these diseases. 

“The international community cannot afford to falter now… When funding falls short, it is the patients – those least able to afford care – who pay the price.”

Tess Hewett, MSF health policy advisor

The consequences of failing to meet the 18 billion USD ($25 billion Canadian) target will be severe and immediate. If countries don’t pledge enough funds, essential work – such as support for data collection systems that monitor disease spikes and where people are getting care – will suffer. Cuts could severely impact the global TB response, as the Global Fund currently supports 76 per cent of the worldwide donor response for TB. In addition, the adoption of promising new tools, such as new TB vaccines, existing malaria vaccines and new HIV prevention tools like lenacapavir, will be limited. 

“The international community cannot afford to falter now,” says Tess Hewett, MSF health policy advisor. “We are seeing major traditional donors signalling deep cuts, even as the need for sustained investment grows. When funding falls short, it is the patients – those least able to afford care – who pay the price.” 

A radiology technician prepares a patient for an X-ray for potential pulmonary tuberculosis (TB) at the MSF-supported Mweso general referral hospital in North Kivu. Democratic Republic of Congo, 2023. © Laora Vigourt/MSF

Insufficient funds shift the burden onto people in vulnerable situations 

Delays in finalizing pledges after Nov. 21 could compromise effective program planning. 

When funding is insufficient, the financial burden is often shifted onto communities in vulnerable situations through an emphasis on increasing “domestic resource mobilization.” While this is envisioned as an increase in health spending by national governments, the reality is this shift frequently results in a hike in out-of-pocket payments by people themselves. This is particularly true in low-income countries.  

MSF physician Abdu Samya Bashagha looks at an X-ray scan of a patient in Abu Sitta Hospital where MSF is running TB support activities. Libya, 2022. © Omar Rashid/MSF

Initial pledges for this replenishment have been deeply concerning. Germany and the UK – the only major traditional donors to pledge so far – have both decreased their commitment compared to the last cycle. Germany has pledged $1.6 billion instead of $2.1 billion and the UK has pledged $1.5 billion instead of $1.8 billion. No donor has increased their pledge when considering inflation.   

If major donors follow Germany and the UK’s example, the results will be catastrophic for people worldwide impacted by TB, HIV and malaria – the world’s top three deadliest, but completely preventable, infectious diseases.

“We urge the remaining big donors to heed the evidence contained in MSF’s Deadly Gaps report and commit fully on Nov. 21,” says Tess Hewett. “To accelerate progress toward Sustainable Development Goal 3 and end TB, HIV and malaria as public health threats, the Global Fund needs the full 18 billion USD ($25 billion Canadian). With the right resources, the Global Fund believes it can save 23 million lives and halve the death toll in just six years.”